Here are the particulars for a person who lacks grace: Once he has turned away from God, the person dwells on himself, and makes self the main goal of his life and activity. This is because at this point, after God, there is for him nothing higher than self, especially because, having previously received every abundance from God and having now forgotten Him, he hurries and takes care to fill himself up with something.
The emptiness that has formed inside him because of his falling away from God causes an unquenchable thirst inside him that is vague but constant. The person has become a bottomless abyss. He makes every effort to fill this abyss, but he cannot see or feel it getting full. Thus, he spends his entire life in sweat, toil and great labors; he busies himself with various occupations in which he hopes to find a way to quench his unquenchable thirst.
These occupations take up all his attention, all his time and all his activity. They are the highest good, in which he lives with his whole heart. Thus, it is clear why a person who makes self his exclusive goal is never himself; instead, everything is outside him, in things either created or acquired by vanity. He has fallen away from God, Who is the fullness of everything. He himself is empty; it remains for him to seemingly pour himself out into an endless variety of things and live in them.
Thus, the sinner thirsts, fusses, and troubles himself with occupations and numerous things outside himself and God. This is why a characteristic trait of sinful life is, in its disregard for salvation, the care and trouble about many things (cf. Lk 10:41).
Taken from "The Path to Salvation" A Manual of Spiritual Transformation By Saint Theophan the Recluse